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Demineralized bone fibers designed for use in bone remodeling
VIA Fill™ was developed utilizing VIVEX’s proprietary Integrity Processing™, where cortical bone fibers are demineralized, exposing the natural bone morphogenic proteins (BMPs) needed for bone formation.1 VIA Fill™ is moldable and comprised of 100% demineralized cortical bone, using an optimized selection of bone fibers of various lengths, without the need for an additional carrier. VIA Fill™ can be used in a number of clinical applications, including spine, cranio-maxillofacial and orthopedics.
Osteoconductive
Maximizes bone forming ability
Osteoinductive
Has osteoinductive potential, which provides exposure of signaling molecules and bone morphogenetic proteins2
VIA Fill™ contains bone fibers, which has been shown to offer improved osteoconductivity when compared to powder due to the increased ability for cells to migrate along fibers, creating “cellular highways” for bone formation.3 VIA Fill™ is supplied in a ready-to-use container and is easily rehydrated with saline. The product’s moldability allows fibers to be shaped into a ball or strip. VIA Fill™ is lyophilized and terminally sterilized SAL 10-6 by e-beam irradiation in final packaging, allowing for convenient storage at ambient temperatures and off the shelf use.
PRODUCT INFORMATION
Preparation Time
Quick rehydration for ease of use in under 4 minutes
Shelf life
Up to 5 years (at ambient temperature of 2°C to 30°C)
Product Composition
100% demineralized cortical bone fibers
Final Preparation
Supplied in a ready-to-use container and can be molded into a ball or strip when rehydrated with saline.
ORDERING INFORMATION
SIZE
CODE
1cc
VFB001
3cc
VFB003
6cc
VFB006
12cc
VFB012
References
1 Urist MR. Bone: formation by autoinduction. Science. 1965;150(3698):893-899.
2 Data on file at VIVEX Biologics.
3 Martin GJ Jr, Boden SD, Titus L, Scarborough NL, “New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis.”, Spine. 1999 Apr 1;24(7):637-45.
2 Data on file at VIVEX Biologics.
3 Martin GJ Jr, Boden SD, Titus L, Scarborough NL, “New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis.”, Spine. 1999 Apr 1;24(7):637-45.
For more information on our VIA Fill™ product,
download our brochure.
download our brochure.
