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Family of medium and large-sized amniotic allografts
VIAGENEX® is a family of amniotic allografts processed to retain the inherent mechanical properties of amniotic tissue and rich supply of extracellular matrix, growth factors and cytokines.1,2 VIAGENEX® may be used as a soft tissue barrier and wound covering in numerous clinical applications, including wound care, burn care, oral surgery, shoulder, nerves, knees, tendons, OB/GYN, and urology.
SUPPORTS HEALING
Provides mechanical protection with endogenous growth factors
INHERENT PROPERTIES OF AMNIOTIC TISSUE
Maintain inherent levels of key extracellular matrix molecules
Retains up to 600+ signaling proteins, including growth factors and cytokines10
Retains up to 600+ signaling proteins, including growth factors and cytokines10
BROADEST VARIETY OF SIZES AND THICKNESSES
Available in 2 thicknesses and medium to large sizes to allow for a variety of applications in the hospital setting
Amniotic-derived tissues may be used as a soft tissue barrier and wound covering that retains endogenous extracellular matrix (ECM), growth factors and cytokines2-5 essential for signaling. The properties of amniotic tissue help provide mechanical protection6 to damaged tissue while retaining nutrient-rich growth factors.7-9
VIAGENEX® is processed using VIVEX’s Integrity Processing™, which retains the intermediate (spongy) layer and preserves the inherent properties of amniotic tissues, maintaining key extracellular matrix molecules, carbohydrates, growth factors and cytokines.7 The proprietary Integrity Processing™ preserves up to 600+ signaling proteins, including growth factors and cytokines.10
VIAGENEX® is available in 2 configurations:
VIAGENEX MATRIX
A flexible, multi-layer allograft maintaining the amnion, its intermediate/spongy layer and the chorion layers of the amniotic sac, providing improved handling and increased workability
VIAGENEX MAX
A maximum natural thickness allograft derived from the umbilical cord membrane and can be sutured
PRODUCT INFORMATION
Preparation Time
None
Shelf life
Up to 5 years (at ambient temperature of 2°C to 30°C)
Product Composition
Amnion, its intermediate/spongy layer and the chorion layers of the amniotic sac
Final Preparation
Tissue allograft
ORDERING INFORMATION
SIZE
CODE
2x6cm
VGM020600S
4x4cm
VGM040400S
4x6cm
VGM040600S
4x8cm
VGM040800S
7x6cm
VGM070600S
2x12cm
VGM021200S
PRODUCT INFORMATION
Preparation Time
None
Shelf life
Up to 5 years (at ambient temperature of 2°C to 30°C)
Product Composition
Umbilical cord membrane
Final Preparation
Tissue allograft
ORDERING INFORMATION
SIZE
CODE
2x3cm
VGC020300S
3x3cm
VGC030300S
3x4cm
VGC030400S
3x5cm
VGC030500S
3x6cm
VGC030600S
3x8cm
VGC030800S
REFERENCES
1 Rowlatt, U. {1979}, Intrauterine wound healing in a 20-week human fetus. Virchows Arch A Pathol Anat Histol, 381(3), 353-361
2 Coolen, N.A. et.al. {2010}. Comparison between human fetal and adult skin. Archives of Dermatological Research, 302(1), 47-55.
3 Coolen NA, Schouten KC, Boekema BK, Middelkoop E, Ulrich MM. Wound healing in a fetal, adult, and scar tissue model: a comparative study. Wound Repair Regen.
2010;18(3):291-301. doi:10.1111/j.1524-475X.2010.00585.x.
2010;18(3):291-301. doi:10.1111/j.1524-475X.2010.00585.x.
4 Tseng SC, Espana EM, Kawakita T, et al. How does amniotic membrane work? Ocul Surf. 2004;2(3):177-187.
5 Riordan NH, George BA, Chandler TB, McKenna RW. Case report of non-healing surgical wound treated with dehydrated human amniotic membrane. J Transl Med. 2015;13:242. doi:10.1186/s12967-015-0608-8.
6 Kim SS, Sohn SK, Lee KY, et al. Use of human amniotic membrane wrap in reducing perineural adhesions in a rabbit model of ulnar nerve neurorrhaphy. J Hand Surg Eur Vol. 2010;35(3):214-219.
doi:10.1177/1753193409352410.
doi:10.1177/1753193409352410.
7 Delcroix GJ, Namin S, D’Ippolito G, Temple HT, Marshall R. Preserving the natural regenerative potential of amniotic membrane. Vivex Biomedical.
8 Niknejad H, Peirovi H, Jorjani M, et al. Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater. 2008;15:88-89.
9 Koob TJ, Lim JJ, Massee M, Zabek N, Denoizièr G. Properties of dehydrated human amnion/chorion composite grafts: implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362. doi:10.1002/jbm.b.33141.
10 Data on file at VIVEX Biologics
For more information on our VIAGENEX® product,
download our brochure.
download our brochure.
